Thanks for your help! I replaced U1 and everything semms normal now, the -5DCV on TP4 disappeared.
However, I followed the Test Guide again and the gain seems lower than expected, when I connect a 1VAC sine to the input and turn the input to max, the LED stays off. Only with gain switch on mid or hight the LED turns green. Same with the output pot to max, the LED only turns red with gain on mid or high... I'm not shure if this is an issue, mybe i just have to wait longer for the tube to warm up...